Synthesis of Amino Acid and Aniline Derivatives of Quinolinediones

Egu, S. A. and Sale, J. F. and Aliyu, A. O. C. and Yahaya, A. and Ocheni, A. (2024) Synthesis of Amino Acid and Aniline Derivatives of Quinolinediones. Journal of Basic and Applied Research International, 29 (5-6). pp. 71-75. ISSN 2395-3446

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Official URL: https://doi.org/10.56557/jobari/2023/v29i5-68569

Abstract

Successful synthesis of amino acid and aniline derivatives of 6,7-dibromo-5,8-quinolinedione is reported. 6,7-Dibromo-5,8-quinolinedione was prepared by nitrosation of 8-hydroxyquinoline, followed by subsequent amination and oxidation of the resulting intermediates. Thereafter, addition of amino acids and anilines supplied the desired products. Effect of solvent on reaction yield and time showed pyridine as the best amongst the studied solvents. Structural elucidation was done using proton NMR and mass spec.

Item Type:	Article
Subjects:	Open Article Repository > Multidisciplinary
Depositing User:	Unnamed user with email support@openarticledepository.com
Date Deposited:	04 Mar 2024 07:45
Last Modified:	04 Mar 2024 07:45
URI:	http://journal.251news.co.in/id/eprint/2023

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