Correlation between Serum Sodium and Potassium Levels in Preeclampsia

Aims: The aim of this study was to find the correlation between serum sodium and serum potassium with preeclampsia.

Study Design: This is a cross sectional study.

Place and Duration of Study: Conducted in Department of Biochemistry in collaboration with the Department of Obstetrics and Gynaecology, (RIMS), Imphal (Manipur) from September 2016 to August 2018.

Methodology: Blood samples of 30 diagnosed patients of preeclampsia and above 18 years of age admitted in the obstetrics antenatal ward of RIMS, Imphal was taken. Samples were analysed for serum sodium and potassium by randox rx imola autoanalyser. The data were analyzed using statistical tools like Chi-square test through SPSS 21.0.

Results: Serum sodium levels were high in 63.34%of study group, low levels were seen in 3.33% followed by normal levels in 33.3%of study group. Serum potassium levels were low in 56.6%of study group, normal in 40% and high in 3.33% of study group. There was positive correlation between serum sodium and proteinuria which was statistically significant at P-value <0.01 and negative correlation was seen between serum potassium levels with proteinuria which was statistically significant at P-value 0.04.

Conclusion: In this study hypernatremia and hypokalaemia were associated with preeclampsia, and may have important causative role in this syndrome therefore constant monitoring of serum sodium and potassium level in pregnant women may help in early detection, management and prevention of preeclampsia.