Relating the Effect of HPA Axis to the Emotional State of Bipolar II Disorder Patient

Using analytic approach we study the effect of HPA axis secretions no the emotional variation of bipolar II disorder patient. Modified Duffing – Van der Pol oscillator was used to model the emotional variation, that was solved analytically using multiple scale perturbation to obtain an asymptotic solution. The solution was graphed to understand the effect of the variation of the cortisol to the oscillator. It was observed that the increase or decrease of the HPA hormone from the basal level in the body system, affects the mood variation of bipolar II disorder patients but not a marker for diagnosis.